HomeBlogEmail Strategy & OptimizationPredictive Email Marketing: Use AI to Boost Open Rates
Email Strategy & Optimization

Predictive Email Marketing: Use AI to Boost Open Rates

Learn how predictive email marketing uses AI to forecast user behavior, optimize send times, and increase engagement. Data-backed strategies inside.

M

Marcus Webb

July 14, 2026

12 min read
HomeBlogEmail Strategy & OptimizationPredictive Email Marketing: Use AI to Boost Open Rates
Email Strategy & Optimization

Predictive Email Marketing: Use AI to Boost Open Rates

Learn how predictive email marketing uses AI to forecast user behavior, optimize send times, and increase engagement. Data-backed strategies inside.

M

Marcus Webb

July 14, 2026

12 min read
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#AI in Email Marketing#Predictive Analytics#Email Personalization#Email Automation
#AI in Email Marketing#Predictive Analytics#Email Personalization#Email Automation
Illustration for predictive email marketing
Illustration for predictive email marketing

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Predictive email marketing is no longer a capability reserved for enterprise teams with data science departments. Any business running an email program today can use AI-driven prediction to send the right message to the right person at precisely the moment they are most likely to act. The result is measurable: AI-driven personalization in email marketing has increased open rates by about 29% and revenue per email by 41%.

That is not a marginal gain. It is the difference between an average program and a high-performing one.


Key Takeaways

  • Machine learning algorithms optimize subject lines to increase open rates by 5 to 10% through pattern recognition and predictive analytics.
  • Sending to each subscriber at their personal optimal time, rather than a fixed batch time, consistently produces 20 to 30% open rate improvements across industries.
  • Segmented email campaigns generate 760% more revenue than non-segmented broadcasts, and the most effective segmentation combines behavioral data with AI-predicted intent scores.
  • Automated emails generate 320% more revenue than non-automated campaigns, with 31% of all email orders originating from automated flows.
  • Email marketing delivers an average return of $36 to $42 per dollar spent, outperforming paid search, social advertising, and display ads.

What Predictive Email Marketing Actually Means

Predictive email marketing applies machine learning and statistical models to your existing customer and campaign data to forecast what a subscriber is likely to do next. It uses AI and behavioral data to forecast what a subscriber will do next, so you can send the right message at the right time and maximize revenue from your owned channel.

This is fundamentally different from standard automation. Traditional email automation follows fixed rules: if someone opens an email, send a follow-up three days later. The current generation of marketing automation makes decisions based on prediction, not rules. Predictive analytics forecasts which leads will buy, which customers will churn, and which campaigns will outperform, usually with 70 to 85% accuracy.

Predictive analytics takes this a step further by training models on historical data. Purchase histories layered with live signals, such as site behavior, give marketing teams the power to more accurately forecast future events.

Stay in the loop

Get the latest posts delivered straight to your inbox. No spam, unsubscribe anytime.

Predictive email marketing is no longer a capability reserved for enterprise teams with data science departments. Any business running an email program today can use AI-driven prediction to send the right message to the right person at precisely the moment they are most likely to act. The result is measurable: AI-driven personalization in email marketing has increased open rates by about 29% and revenue per email by 41%.

That is not a marginal gain. It is the difference between an average program and a high-performing one.


Key Takeaways

  • Machine learning algorithms optimize subject lines to increase open rates by 5 to 10% through pattern recognition and predictive analytics.
  • Sending to each subscriber at their personal optimal time, rather than a fixed batch time, consistently produces 20 to 30% open rate improvements across industries.
  • Segmented email campaigns generate 760% more revenue than non-segmented broadcasts, and the most effective segmentation combines behavioral data with AI-predicted intent scores.
  • Automated emails generate 320% more revenue than non-automated campaigns, with 31% of all email orders originating from automated flows.
  • Email marketing delivers an average return of $36 to $42 per dollar spent, outperforming paid search, social advertising, and display ads.

What Predictive Email Marketing Actually Means

Predictive email marketing applies machine learning and statistical models to your existing customer and campaign data to forecast what a subscriber is likely to do next. It uses AI and behavioral data to forecast what a subscriber will do next, so you can send the right message at the right time and maximize revenue from your owned channel.

This is fundamentally different from standard automation. Traditional email automation follows fixed rules: if someone opens an email, send a follow-up three days later. The current generation of marketing automation makes decisions based on prediction, not rules. Predictive analytics forecasts which leads will buy, which customers will churn, and which campaigns will outperform, usually with 70 to 85% accuracy.

Predictive analytics takes this a step further by training models on historical data. Purchase histories layered with live signals, such as site behavior, give marketing teams the power to more accurately forecast future events.

The practical output is a system that treats each subscriber as an individual rather than a member of a broad list segment.


The Four Core Applications of Predictive Email Marketing

1. Send-Time Optimization

Blasting your entire list at 10 AM on a Tuesday is one of the most reliably suboptimal things you can do in email marketing. By analyzing when individual users have historically opened and engaged with your emails, the system can determine the optimal delivery time for each person on your list. Instead of sending a campaign to everyone at once, the system staggers the delivery to ensure each email arrives at the moment the recipient is most likely to see and interact with it.

Powered by Journey AI, Adobe Campaign can analyze and predict open rates, optimal send times, and probable churn based on historical engagement metrics. Platforms like Klaviyo, Mailchimp, and HubSpot now include comparable send-time optimization as a built-in feature.

2. Predictive Segmentation

Standard segmentation groups subscribers by demographics or past actions. Predictive segmentation groups them by future behavior. By analyzing patterns in customer data, predictive models can identify micro-segments of users with similar predicted behaviors, such as "high-value customers likely to churn" or "new subscribers likely to make their first purchase within a week." This allows you to send highly targeted messages that address the specific needs and motivations of each group.

Hyper-segmented campaigns targeting micro-audiences of 500 to 2,000 contacts outperform broad segments by 3.4x on conversion rate.

For a deeper look at how to build these audiences effectively, see our guide to email list segmentation strategies that boost ROI by 760%.

3. Predictive Lead Scoring

Predictive lead scoring uses AI and machine learning to analyze past data and identify leads most likely to convert. Unlike static rules such as assigning points for email opens, it learns from customer behavior patterns to make smarter decisions.

The output is a score that reflects conversion probability. This score, usually between 0 and 100, reflects how likely a lead is to become a customer. High scorers, from 80 to 100, show strong buying signals and are ready for sales outreach. Medium scorers, 50 to 79, show some interest but may need more nurturing. Low scorers, 0 to 49, are not engaged or unlikely to convert right now.

High-scoring leads can boost conversion rates by 38%. When a lead's score crosses a defined threshold, predictive platforms can automatically shift them into a different email nurture track, alert sales, or change what content they receive, without any manual intervention.

4. Churn Prediction and Win-Back Campaigns

Losing a customer is often more costly than acquiring a new one. Predictive analytics provides a powerful tool for identifying customers who are at risk of churning. Models can analyze engagement data, purchase frequency, and customer service interactions to assign a "churn risk" score to each subscriber.

If a customer's churn probability reaches a certain threshold, the system can automatically trigger a win-back campaign with a personalized discount or special offer.

The practical output is a system that treats each subscriber as an individual rather than a member of a broad list segment.


The Four Core Applications of Predictive Email Marketing

1. Send-Time Optimization

Blasting your entire list at 10 AM on a Tuesday is one of the most reliably suboptimal things you can do in email marketing. By analyzing when individual users have historically opened and engaged with your emails, the system can determine the optimal delivery time for each person on your list. Instead of sending a campaign to everyone at once, the system staggers the delivery to ensure each email arrives at the moment the recipient is most likely to see and interact with it.

Powered by Journey AI, Adobe Campaign can analyze and predict open rates, optimal send times, and probable churn based on historical engagement metrics. Platforms like Klaviyo, Mailchimp, and HubSpot now include comparable send-time optimization as a built-in feature.

2. Predictive Segmentation

Standard segmentation groups subscribers by demographics or past actions. Predictive segmentation groups them by future behavior. By analyzing patterns in customer data, predictive models can identify micro-segments of users with similar predicted behaviors, such as "high-value customers likely to churn" or "new subscribers likely to make their first purchase within a week." This allows you to send highly targeted messages that address the specific needs and motivations of each group.

Hyper-segmented campaigns targeting micro-audiences of 500 to 2,000 contacts outperform broad segments by 3.4x on conversion rate.

For a deeper look at how to build these audiences effectively, see our guide to email list segmentation strategies that boost ROI by 760%.

3. Predictive Lead Scoring

Predictive lead scoring uses AI and machine learning to analyze past data and identify leads most likely to convert. Unlike static rules such as assigning points for email opens, it learns from customer behavior patterns to make smarter decisions.

The output is a score that reflects conversion probability. This score, usually between 0 and 100, reflects how likely a lead is to become a customer. High scorers, from 80 to 100, show strong buying signals and are ready for sales outreach. Medium scorers, 50 to 79, show some interest but may need more nurturing. Low scorers, 0 to 49, are not engaged or unlikely to convert right now.

High-scoring leads can boost conversion rates by 38%. When a lead's score crosses a defined threshold, predictive platforms can automatically shift them into a different email nurture track, alert sales, or change what content they receive, without any manual intervention.

4. Churn Prediction and Win-Back Campaigns

Losing a customer is often more costly than acquiring a new one. Predictive analytics provides a powerful tool for identifying customers who are at risk of churning. Models can analyze engagement data, purchase frequency, and customer service interactions to assign a "churn risk" score to each subscriber.

If a customer's churn probability reaches a certain threshold, the system can automatically trigger a win-back campaign with a personalized discount or special offer.

Frequency modeling that adjusts sends per subscriber based on engagement levels reduces unsubscribe rates by 15 to 25% while maintaining or growing revenue per subscriber. This protects your list quality and your sender reputation at the same time.


How AI Predicts Which Subject Lines Will Drive Opens

Subject lines are where predictive email marketing has the most immediate, visible impact for most teams. Organizations using AI to generate and optimize subject lines see a 26% increase in open rates compared to manually written alternatives.

AI does not guess. It analyzes your historical campaign data to identify which linguistic patterns, length ranges, personalization elements, and phrasing styles have driven the highest open and click rates for specific audience segments. It then applies those patterns to new campaigns and continues to refine its recommendations as more data comes in.

The compounding effect is significant. The performance advantage of the dual-engine approach comes from a multiplicative effect. Send-time optimization might lift open rates 20 to 30%. Personalized subject lines might lift open rates another 15 to 20%. Personalized body copy might lift click-through rates 10 to 15%.

Each gain compounds on the previous one. A team using all three levers simultaneously does not simply add the improvements together; they multiply.

For practical guidance on subject line construction before applying AI optimization, the principles in our email subject line best practices guide remain foundational.


Customer Lifetime Value Forecasting in Email Campaigns

One of the most underutilized applications of predictive email marketing is customer lifetime value (CLV) forecasting. Rather than treating every subscriber identically, CLV models let you calibrate your investment in each contact.

AI predicts what each customer will be worth over 12 to 24 months based on their first 30 days of behavior. Marketing teams use this to set acquisition cost ceilings per segment. A customer predicted to spend $5,000 lifetime can justify a $400 acquisition cost.

Organizations that replace static customer segmentation with dynamic CLV prediction see measurable revenue uplift because they can allocate retention spending proportionally to predicted customer value. Instead of treating all customers equally, AI models identify which customers will generate the most future revenue and which retention interventions produce the highest return.

In practice, this means your high-CLV segment might receive exclusive early-access campaigns, VIP onboarding sequences, or loyalty incentives, while lower-CLV subscribers receive lower-touch, higher-volume sequences optimized for a different conversion path.


Tools That Power Predictive Email Marketing

You do not need to build a data science team to access these capabilities. Several major platforms have embedded predictive features directly into their products.

Frequency modeling that adjusts sends per subscriber based on engagement levels reduces unsubscribe rates by 15 to 25% while maintaining or growing revenue per subscriber. This protects your list quality and your sender reputation at the same time.


How AI Predicts Which Subject Lines Will Drive Opens

Subject lines are where predictive email marketing has the most immediate, visible impact for most teams. Organizations using AI to generate and optimize subject lines see a 26% increase in open rates compared to manually written alternatives.

AI does not guess. It analyzes your historical campaign data to identify which linguistic patterns, length ranges, personalization elements, and phrasing styles have driven the highest open and click rates for specific audience segments. It then applies those patterns to new campaigns and continues to refine its recommendations as more data comes in.

The compounding effect is significant. The performance advantage of the dual-engine approach comes from a multiplicative effect. Send-time optimization might lift open rates 20 to 30%. Personalized subject lines might lift open rates another 15 to 20%. Personalized body copy might lift click-through rates 10 to 15%.

Each gain compounds on the previous one. A team using all three levers simultaneously does not simply add the improvements together; they multiply.

For practical guidance on subject line construction before applying AI optimization, the principles in our email subject line best practices guide remain foundational.


Customer Lifetime Value Forecasting in Email Campaigns

One of the most underutilized applications of predictive email marketing is customer lifetime value (CLV) forecasting. Rather than treating every subscriber identically, CLV models let you calibrate your investment in each contact.

AI predicts what each customer will be worth over 12 to 24 months based on their first 30 days of behavior. Marketing teams use this to set acquisition cost ceilings per segment. A customer predicted to spend $5,000 lifetime can justify a $400 acquisition cost.

Organizations that replace static customer segmentation with dynamic CLV prediction see measurable revenue uplift because they can allocate retention spending proportionally to predicted customer value. Instead of treating all customers equally, AI models identify which customers will generate the most future revenue and which retention interventions produce the highest return.

In practice, this means your high-CLV segment might receive exclusive early-access campaigns, VIP onboarding sequences, or loyalty incentives, while lower-CLV subscribers receive lower-touch, higher-volume sequences optimized for a different conversion path.


Tools That Power Predictive Email Marketing

You do not need to build a data science team to access these capabilities. Several major platforms have embedded predictive features directly into their products.

  • Klaviyo: Klaviyo specializes in AI for e-commerce, with a built-in CDP that includes predictive AI for churn risk, customer lifetime value, and next-order-date forecasting.
  • HubSpot: HubSpot provides predictive lead scoring combined with lifecycle automation.
  • Braze: Braze orchestrates personalized experiences using AI that predicts individual-level churn probability and purchase likelihood. Its Canvas Flow automatically routes customers through the most effective journey based on real-time behavior and predictive scores.
  • Mailchimp: Offers AI-assisted send-time optimization and content recommendation tools.
  • Adobe Campaign: Powered by Journey AI, it can analyze and predict open rates, optimal send times, and probable churn based on historical engagement metrics.

When evaluating any platform, ask three questions: How often is the predictive model retrained? What data inputs drive each prediction? Can it explain why a subscriber received a specific score? The accuracy of predictive analytics in email marketing depends on the predictive model, since it is only as good as the data it is fed. Before trusting the predictions, audit the data sources for accuracy, completeness, and consistency.

For a broader look at how autonomous AI is reshaping campaign management, our guide on AI email marketing personalization techniques covers the tactical layer in detail.


How to Implement Predictive Email Marketing: A Practical Starting Point

Getting started does not require a full platform overhaul. Getting started with predictive analytics does not require a complete overhaul of your current email marketing strategy. It can be implemented in phases, allowing marketers to test the waters before scaling up.

A practical sequence:

  • Klaviyo: Klaviyo specializes in AI for e-commerce, with a built-in CDP that includes predictive AI for churn risk, customer lifetime value, and next-order-date forecasting.
  • HubSpot: HubSpot provides predictive lead scoring combined with lifecycle automation.
  • Braze: Braze orchestrates personalized experiences using AI that predicts individual-level churn probability and purchase likelihood. Its Canvas Flow automatically routes customers through the most effective journey based on real-time behavior and predictive scores.
  • Mailchimp: Offers AI-assisted send-time optimization and content recommendation tools.
  • Adobe Campaign: Powered by Journey AI, it can analyze and predict open rates, optimal send times, and probable churn based on historical engagement metrics.

When evaluating any platform, ask three questions: How often is the predictive model retrained? What data inputs drive each prediction? Can it explain why a subscriber received a specific score? The accuracy of predictive analytics in email marketing depends on the predictive model, since it is only as good as the data it is fed. Before trusting the predictions, audit the data sources for accuracy, completeness, and consistency.

For a broader look at how autonomous AI is reshaping campaign management, our guide on AI email marketing personalization techniques covers the tactical layer in detail.


How to Implement Predictive Email Marketing: A Practical Starting Point

Getting started does not require a full platform overhaul. Getting started with predictive analytics does not require a complete overhaul of your current email marketing strategy. It can be implemented in phases, allowing marketers to test the waters before scaling up.

A practical sequence:

  1. Clean your data first. Before implementing any predictive feature, clean and update your email database. Accurate and applicable historical data is the bedrock for effective predictive models.
  2. Start with send-time optimization. It is the lowest-friction change and produces measurable results quickly. Run an A/B test comparing predictive send times against your current fixed schedule.
  3. Build behavioral micro-segments. Use predictive insights to identify and segment your audience beyond simple demographics. Create segments based on predicted behaviors, such as "most likely to purchase in the next 30 days," "at-risk churners," or "high-value content engagers."
  4. Automate churn detection. Set a churn probability threshold that triggers your re-engagement sequence automatically.
  5. Measure revenue per recipient, not just open rates. Track revenue per recipient, customer lifetime value, and churn to keep the model learning and improving.
  1. Clean your data first. Before implementing any predictive feature, clean and update your email database. Accurate and applicable historical data is the bedrock for effective predictive models.
  2. Start with send-time optimization. It is the lowest-friction change and produces measurable results quickly. Run an A/B test comparing predictive send times against your current fixed schedule.
  3. Build behavioral micro-segments. Use predictive insights to identify and segment your audience beyond simple demographics. Create segments based on predicted behaviors, such as "most likely to purchase in the next 30 days," "at-risk churners," or "high-value content engagers."
  4. Automate churn detection. Set a churn probability threshold that triggers your re-engagement sequence automatically.
  5. Measure revenue per recipient, not just open rates. Track revenue per recipient, customer lifetime value, and churn to keep the model learning and improving.

One important caution: always apply human review to AI-generated campaign outputs. AI-generated subject lines perform well on average but occasionally produce off-brand, misleading, or tone-inappropriate outputs. Every production deployment of generative email content should include a human review step before send, particularly for high-stakes campaigns to large segments.


Common Mistakes That Undermine Predictive Results

The technology works, but poor implementation neutralizes the gains.

Automating broken processes. If your current lead handoff or segmentation logic has structural problems, predictive models will execute those problems at scale and with greater speed.

Trusting model outputs without testing. Predictive analytics forecasts which leads will buy, which customers will churn, and which campaigns will outperform, usually with 70 to 85% accuracy. That remaining margin matters. Always measure AI-optimized campaigns against a control group.

Ignoring data privacy compliance. AI email marketing must comply with data privacy and security regulations like GDPR and CCPA. These regulations restrict automated decision-making and require transparency about how customer information is collected and used.

Over-relying on open rates as the primary success metric. Email marketers now prioritize click-through rates, click-to-open rates, and conversion metrics over open rates when evaluating campaign performance, partly due to Apple Mail Privacy Protection inflating raw open figures. Revenue per email and click-to-open rate are more reliable measures of whether predictive optimization is actually working.


Frequently Asked Questions

What is predictive email marketing?

Predictive email marketing uses machine learning models to analyze historical subscriber behavior and forecast future actions, such as who is likely to open an email, convert, or unsubscribe. Predictive analytics in marketing uses historical data, statistical algorithms, and machine learning to forecast future customer behavior. These forecasts are then used to personalize send times, content, subject lines, and campaign sequences for each individual subscriber.

How much can predictive email marketing improve open rates?

Organizations using AI to generate and optimize subject lines see a 26% increase in open rates compared to manually written alternatives. Send-time optimization alone produces 20 to 30% open rate improvements across industries when emails are delivered at each subscriber's personal optimal time rather than a fixed batch window. Combining both levers compounds the gains further.

Do I need a large email list to use predictive email marketing?

At minimum, you need 12 to 24 months of historical data showing customer behaviors and the outcomes you want to predict. List size matters less than data depth. A list of 5,000 highly engaged subscribers with rich behavioral history will produce more accurate predictions than a list of 50,000 subscribers with thin interaction data. Most modern ESPs with built-in predictive features handle the modeling automatically once sufficient data exists.

What is the biggest risk of using AI for email personalization?

One important caution: always apply human review to AI-generated campaign outputs. AI-generated subject lines perform well on average but occasionally produce off-brand, misleading, or tone-inappropriate outputs. Every production deployment of generative email content should include a human review step before send, particularly for high-stakes campaigns to large segments.


Common Mistakes That Undermine Predictive Results

The technology works, but poor implementation neutralizes the gains.

Automating broken processes. If your current lead handoff or segmentation logic has structural problems, predictive models will execute those problems at scale and with greater speed.

Trusting model outputs without testing. Predictive analytics forecasts which leads will buy, which customers will churn, and which campaigns will outperform, usually with 70 to 85% accuracy. That remaining margin matters. Always measure AI-optimized campaigns against a control group.

Ignoring data privacy compliance. AI email marketing must comply with data privacy and security regulations like GDPR and CCPA. These regulations restrict automated decision-making and require transparency about how customer information is collected and used.

Over-relying on open rates as the primary success metric. Email marketers now prioritize click-through rates, click-to-open rates, and conversion metrics over open rates when evaluating campaign performance, partly due to Apple Mail Privacy Protection inflating raw open figures. Revenue per email and click-to-open rate are more reliable measures of whether predictive optimization is actually working.


Frequently Asked Questions

What is predictive email marketing?

Predictive email marketing uses machine learning models to analyze historical subscriber behavior and forecast future actions, such as who is likely to open an email, convert, or unsubscribe. Predictive analytics in marketing uses historical data, statistical algorithms, and machine learning to forecast future customer behavior. These forecasts are then used to personalize send times, content, subject lines, and campaign sequences for each individual subscriber.

How much can predictive email marketing improve open rates?

Organizations using AI to generate and optimize subject lines see a 26% increase in open rates compared to manually written alternatives. Send-time optimization alone produces 20 to 30% open rate improvements across industries when emails are delivered at each subscriber's personal optimal time rather than a fixed batch window. Combining both levers compounds the gains further.

Do I need a large email list to use predictive email marketing?

At minimum, you need 12 to 24 months of historical data showing customer behaviors and the outcomes you want to predict. List size matters less than data depth. A list of 5,000 highly engaged subscribers with rich behavioral history will produce more accurate predictions than a list of 50,000 subscribers with thin interaction data. Most modern ESPs with built-in predictive features handle the modeling automatically once sufficient data exists.

What is the biggest risk of using AI for email personalization?

The main risks are data quality and lack of human oversight. AI email marketing models need engagement history, CRM data, intent signals, and technographic profiles to produce reliable predictions. Data quality is the limiting factor, not the AI itself; models perform only as well as the data feeding them. Without regular human review of AI-generated content and model outputs, campaigns can produce off-brand messaging or optimize for the wrong outcome entirely, as when a churn model stops emailing new subscribers because they churn at higher rates than veterans.

How does predictive email marketing differ from standard email automation?

Standard automation triggers emails based on fixed rules, for example, "send a welcome email one hour after signup." Predictive marketing replaces those fixed rules with probability-based decisions. Predictive analytics and marketing automation are highly complementary. Predictive analytics generates intelligence: scores, forecasts, and recommendations. Marketing automation platforms use this intelligence to trigger personalized actions automatically. The result is a system that adapts to individual subscriber behavior in real time rather than following a predetermined script. For teams building these automated flows, the email marketing automation tips guide covers the execution layer in detail.

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The main risks are data quality and lack of human oversight. AI email marketing models need engagement history, CRM data, intent signals, and technographic profiles to produce reliable predictions. Data quality is the limiting factor, not the AI itself; models perform only as well as the data feeding them. Without regular human review of AI-generated content and model outputs, campaigns can produce off-brand messaging or optimize for the wrong outcome entirely, as when a churn model stops emailing new subscribers because they churn at higher rates than veterans.

How does predictive email marketing differ from standard email automation?

Standard automation triggers emails based on fixed rules, for example, "send a welcome email one hour after signup." Predictive marketing replaces those fixed rules with probability-based decisions. Predictive analytics and marketing automation are highly complementary. Predictive analytics generates intelligence: scores, forecasts, and recommendations. Marketing automation platforms use this intelligence to trigger personalized actions automatically. The result is a system that adapts to individual subscriber behavior in real time rather than following a predetermined script. For teams building these automated flows, the email marketing automation tips guide covers the execution layer in detail.

No comments yet. Be the first!

Leave a comment

Comments are reviewed before publishing.

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